Posted to MedZilla on 1/20/2019

Takeda Pharmaceuticals

US-MA, Research Scientist II R0006520-MZ


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Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Research Scientist II in our Cambridge office.
Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Research Scientist II working on the Immuno Oncology team, you will be empowered to initiate investigation of new experimental approaches and , and contribute to functional problem resolution and objective setting a typical day will include:


Based in Cambridge, MA, a research-based role under general supervision, performing a variety of routine and specialized in vivo experimental procedures for the purpose of research in the Immuno-Oncology (I/O) field. The scientist will work in a highly matrixed and collaborative environment that relies on the close interactions with the entire I/O biology research team. The scientist will provide theoretical/conceptual input to the design, development and execution of research assignments within the area of expertise, potentially contributing to multiple projects. The candidate will be responsible for designing (in-life studies), executing, analyzing (in vitro immune-based assays) and interpreting well-controlled studies to advance Immuno-Oncology programs. In addition, the candidate will continue to explore and introduce new technological tools and/or methodology to further expand the group s immune-related technical capabilities.


  • Initiates investigation of new experimental approaches to a wide range of problems using scientific theory and technical literature.
  • Identifies, plans and executes novel scientific projects and may manage the work of others a direct or matrixed structure
  • Contributes to functional problem resolution and objective setting
  • Contributes to functional scientific discussion
  • Uses defined practices and theoretical knowledge to perform analysis, interpret results from complex experiments and determine appropriate action
  • Utilizes relevant information, technology and resources, contributing to complex team problem resolution and objectives
  • Utilizes specialized laboratory instrument and data analysis.
  • Prepares and presents comprehensive technical or project reports and formal presentations / posters to full range of internal/external audiences
  • Contributes to the team and work collaboratively across different function.
  • Develops and troubleshoots experimental procedures if results are unexpected and suggesting alternative routines to crosscheck own findings.
  • Performs in vitro and in vivo techniques/procedures typically required for laboratory/study such as, but not limited to, isolation of primary cells from various tissues and perform antibody staining for FACS-based analysis, qPCR, transcriptional profiling), in vivo tumor models
  • Assists with planning and execution of specific research procedures, coordinates schedules of experiments and procedures.
  • Maintains accurate records of results and methodologies and documenting them.
  • Takes on some administrative tasks.


  • Ph.D. degree with 2+ years of experience. Bachelor s degree in a scientific discipline, or equivalent with 10 + years of experience, or Master's degree in a scientific discipline, or equivalent with 8+ years of experience
  • Demonstrates knowledge of theories, principles, and concepts typically acquired through completion of biology-related degree.
  • Acts as the recognized scientific resource on an aspect of a program.
  • Demonstrates effective project engagement skills.
  • Hands-on experience in Industry (preferred) setting with solid track record of simultaneous support of multiple programs and able to work well across multi-functional groups.
  • Hands on experience working with in vivo murine/NHP model(s) as it pertains to T-helper cell and other immune cell biology, as well as various humanized mouse model(s).
  • High level of proficiency in complex tissue dissection and isolation of rare tissue resident immune cell population(s).
  • Primary (human, rodent, and non-human primate) immune cell culture experience and downstream manipulation such as, but not limited to, immune cell-activation and -suppression assays and CRISPR-mediated gene editing.
  • Independently designs and executes on experimental studies based on small molecules and antibodies
  • Hands on experience on flow-cytometry is preferred, but not required.
  • Self-driven and proven ability to learn new techniques and tackle new science.
  • Excellent organizational skills. Excellent written, communication, and interpersonal skills
  • Keeps current with emerging trends in discipline.


  • None required


  • Manual dexterity required to operate office and lab equipment
  • Carrying, handling and reaching for objects up to 25 lbs
  • Prolonged standing and/or sitting
  • Exposure to hazardous/toxic/dangerous chemicals and biohazards

401(k) with company match and Annual Retirement Contribution Plan
Tuition reimbursement
Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs
Empowering Our People to Shine
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Boston, MA

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Full time

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