Posted to MedZilla on 4/19/2018

Takeda Pharmaceuticals

US-MA, Immunology-Oncology Biology Senior Scientist II / I, Immune Profiling R0000304-MZ


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Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as an Immunology-Oncology Biology Senior Scientist II / I, Immune Profiling in our location office.
Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Senior Scientist II / I working on the Immunology Research team, you will be empowered to support deep immunoprofiling and single-cell sorting for Immuno-Oncology programs and interpret datasets involving high-throughput genomic and immune-profiling data, and a typical day will include:
POSITION OBJECTIVES:Based in Cambridge, MA, this research scientist will leverage a cutting-edge flow cytometry platform for support of Immuno-Oncology programs in Takeda. In addition the candidate will continue to explore and introduce new technological tools to further expand a world-class immunology group. The candidate will experimentally evaluate/explore (i) mechanisms of action, (ii) various combinatorial therapies, (iii) immune biomarkers and (iv) therapeutic response in pre-clinical setting. He/She will also contribute scientific know-how and expertise in immunology and will develop strategies, explore hypotheses and interpret datasets involving high-throughput genomic and immune-profiling data.


  • Reports to Assoc. Dir. Immunology/Head of Immune Profiling Immunology Unit Boston.
  • Leverages a world-class flow cytometry facility in Boston to support deep immunoprofiling and single-cell sorting for Immuno-Oncology programs through to clinical proof-of-mechanism.
  • Spends ~ 85% of time in laboratory to maintain and implement a world-class immunoprofiling platform and assist in downstream experimental assays.
  • Integrates this platform with bioinformatics and genetics approaches (including profiling approaches such as Nanostring), by leveraging internal expertise in Takeda in combination with academic partners and CROs.
  • Serves as a liaison for immunoprofiling in the Immunology Unit, establishing best practices and scientifically rigorous standards for procedures, data management, and data interpretation.
  • Assists in the identification, advancement, and success of innovative external partnerships for Immuno-Oncology.
  • Provides immunological expertise for Immuno-Oncology programs as appropriate.
  • Plays a key role in translational research activities, including biomarker discovery and validation.
  • Keeps up with the up-to-date scientific advancement (e.g. systems approach to identify immune signatures, not limited to, T cell clonotype analysis in blood or tissues, mass spectrometry, and single-cell gene expression analysis).


  • PhD in Immunology
  • 4-5 years postdoctoral hands-on work carried out in world-renowned Immunology / Immuno-Oncology lab
  • Publication record in top scientific journals (International reputation)
  • Expert in high-definition flow cytometry instrumentation, assay development, and data analysis
  • Minimum 1-2 years of hands-on experience in Industry setting with track record of contributing deep immuno-profiling support to programs and able to work well across multi-functional groups.


  • Requires approximately 10% travel, including international


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

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Cambridge, MA

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