Posted to MedZilla on 3/18/2018

Takeda Pharmaceuticals

US-MA, Scientist, Pharmaceutics Research 1703044-MZ


Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Scientist, Pharmaceutics Research in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Scientist working on the Pharmaceutics Research team, you will be empowered to lead technical activities and represent Pharmaceutical Research on a cross-functional team, and a typical day will include:

  • Support the transition of novel compounds from Discovery into Development and continued research efforts during the developmental lifecycle of compounds.
  • Significant interaction with Discovery Teams, Drug Safety , DMPK and close collaboration with Process Chemistry, Formulation development and Analytical Development to achieve project goals.
  • Independently designs and executes detailed studies on new development candidates to elucidate fundamental physicochemical properties and behaviors that enable lead candidate selection and downstream CMC development.
  • Responsible for significant or sole technical leadership within a project and provides theoretical/conceptual input to multiple projects within the department or Pharmaceutical Sciences Division
  • Contributes to a cross-functional Pharmaceutical Sciences team responsible for overseeing API salt and polymorph selection and subsequent development activities
  • Develops non-GLP and GLP formulations based on the physical chemical properties of molecules and their route of delivery to support pre-clinical studies.
  • Conducts biorelevant in vitro studies to assess potential in-vivo performance/impact of API and drug product during development lifecycle
  • Interfaces with individual Pharmaceutical Science colleagues and cross functional project teams to ensure that development activities are consistent with physicochemical properties
  • Represents functional area on cross functional teams communicating Pharmaceutics Research activities and milestones
  • Participates on Discovery Teams and collaborates with Drug Safety and DMPK to evaluate the developability of molecules in late Lead Optimization.
  • Collaborates with Drug Safety to transfer formulations to CRO s for non-GLP and GLP toxicology studies
  • Responsible for integrating scientific/technical efforts around cross functional issues
  • Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders
  • Plans and implements resolutions to technical problems/issues
  • Supports local and global initiatives which may include leading initiatives or work streams


Education and Experience:

  • PhD in Pharmaceutics, physical organic chemistry, pharmacy, or related pharmaceutical science; 0-1 years relevant industry experience
  • PhD: Demonstrated mastery of subject or area related to field
Knowledge and Skills:
  • Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
  • Teamwork -- Ability to work well in highly cross functional team environment and across global line functions.
  • Communication Skills -Able to expresses one s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents
  • Organization Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
  • Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
  • Resource Management -Ability to manage one s time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
  • Technical - strong knowledge of physicochemical and preclinical formulation theory along with experience in multiple analytical techniques (DSC, TGA, HPLC, XRPD, Raman, etc) and proven ability to work in a lab setting


  • May require approximately 5-10% travel.


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

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Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visit

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